Directions for use: for best results apply to areas of pain liberally morning and night for at least 15 consecutive days. A gentle tingling sensation on the skin may occur, this is normal, however, if irritation occurs discontinue use. Some separation of contents can occur at higher temperatures, this is normal. To avoid keep refrigerated at temperatures of 23C or above. Note: this product has not been tested with regard to any medical contraindications or its safety during pregnancy or whilst breastfeeding.